DNA TEST - HISTAMINE INTOLERANCE REPORT

Histamine is a chemical that is released by white blood cells into the bloodstream when the immune system is defending against a potential allergen. This release can result in an allergic reaction from triggers such as pollen, mold, and certain foods. Histamine has many important and diverse biological functions: it protects against infection, regulates physiological functions in the gut, and acts as a neurotransmitter.

Once formed, histamine is either stored or rapidly inactivated by its primary degradative enzymes - diamine oxidase (DAO) in the gut, and histamine-n-methyltransferase (HNMT) in the nervous system and lungs. Histamine degradation is altered by genetics and environmental factors. Impaired histamine degradation can result in histamine toxicity and numerous symptoms that mimic an allergic reaction: • Skin: itchiness, redness, rash, eczema, hives • Gastro-intestinal tract: stomach acid reflux, diarrhoea, nausea, vomiting • Respiratory: runny nose, broncho-constriction, asthma, chronic cough, nasal congestion • Vascular: vasodilation, low blood pressure, dizziness, fainting, rapid heart beat, oedema, migraine/headaches • Neurological: insomnia, anxiety, memory and concentration problems, ADHD Because of its multifaceted symptoms, histamine intolerance is frequently underestimated, or its symptoms misinterpreted as they are often mistaken for a food allergy or a gastrointestinal disorder.

This report describes the genes, nutrients, and lifestyle and environmental factors that can impact histamine degradation. It provides a personalised summary pathway and detailed results, followed by a generic histamine intolerance guide